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The History of ADHD Treatments
Overview:
Effective and Well Tolerated
Stimulants are the most commonly prescribed ADHD treatment
Stimulants are generally considered effective and well tolerated medications
Up to 80% of children with ADHD respond well to stimulant medications
The medicine in CONCERTA®, methylphenidate, has been used for over 50 years
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The History of ADHD Treatments
Effective and Well Tolerated
Stimulants are the most commonly prescribed ADHD treatment
Stimulants are generally considered effective and well tolerated medications
Up to 80% of children with ADHD respond well to stimulant medications
The medicine in CONCERTA®, methylphenidate, has been used for over 50 years
The most commonly prescribed treatments for ADHD today are from a class of drugs called stimulants. When used under medical supervision, stimulants are considered effective and well tolerated for most children with ADHD. In fact, stimulants are the most widely studied group of medications for ADHD.
Stimulants are proven to improve ADHD symptoms, including inattention, impulsivity, and hyperactivity. Studies show that about 80% of children with ADHD respond well to stimulants.
Stimulants are thought to affect the way the brain regulates attention and movement. Stimulants work to enhance the availability of the brain's chemical messengers, dopamine and norepinephrine. These messengers are believed to play a role in behaviors like attention and movement.
The most common side effects of stimulants in children include decreased appetite, weight loss, nervousness and insomnia. In most situations, side effects can be successfully managed through adjustments in dose or schedule of medication.
Stimulants, such as CONCERTA®, are recommended among first-line therapies as part of a total treatment program for the treatment of ADHD by the American Academy of Pediatrics. Methylphenidate, the medicine in CONCERTA®, has been used for over 50 years.
CONCERTA® is well tolerated in clinical studies. The most common adverse reaction was upper abdominal pain (5.9%). Less than 3% of children and adolescents experienced insomnia. Less than 1% experienced a loss of appetite. Less than 1% experienced moodiness.
CONCERTA® is a prescription product approved for the treatment of attention deficit hyperactivity disorder (ADHD) as part of a total treatment program that may include counseling or other therapies.
IMPORTANT SAFETY INFORMATION
Talk to your healthcare professional for a proper diagnosis and treatment of ADHD. Only a healthcare professional can decide whether medication is right for you or your child.
CONCERTA® should not be taken by patients who have: allergies to methylphenidate or other ingredients in CONCERTA®; significant anxiety, tension, or agitation; glaucoma; tics, Tourette's syndrome, or family history of Tourette's syndrome; current or past use of monoamine oxidase inhibitor (MAOI); esophagus, stomach, or intestinal narrowing. Children under 6 years of age should not take CONCERTA®.
Abuse of methylphenidate may lead to dependence. Tell your healthcare professional if you or your child has had problems with alcohol or drugs; has had any heart problems, heart defects, high blood pressure, or a family history of these problems; has had depression, abnormal thoughts or visions, bipolar disorder, or seizure. Contact your healthcare professional immediately if you or your child: develops abnormal thinking or hallucinations, abnormal or extreme moods and/or excessive activity; or if aggressive behavior or hostility develops or worsens while taking CONCERTA®. Your child's healthcare professional should check height and weight often and may interrupt CONCERTA® treatment if your child is not growing or gaining weight as expected.
Stimulants may impair the ability of the patient to operate potentially hazardous machinery or vehicles. Caution should be used accordingly until you are reasonably certain that CONCERTA® does not adversely affect your ability to engage in such activities.
The most common adverse reaction (>5%) reported in children and adolescents was upper abdominal pain. The most common adverse reactions (>10%) reported in adults were dry mouth, nausea, decreased appetite, headache, and insomnia.
CONCERTA® and OROS® are registered trademarks of ALZA Corporation
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